Pipeline

Pipeline Development

Novel Diagnostics & Innovative Therapeutics

Zomedica’s diagnostic pipeline aims to help veterinarians and their teams get better answers, faster via breakthrough technologies and by improving existing tests to accelerate speed to results while increasing sensitivity, specificity, performance and overall affordability.

Zomedica’s therapeutic pipeline is based on human approved drug formulations or compounded formulations that veterinarians already use to treat their patients. Zomedica’s therapeutic candidates are being formulated for animal physiology, tested for safety and efficacy, and submitted to the FDA Center for Veterinary Medicine (FDA-CVM) for approval.

Diagnostic Pipeline

Assay Development

Verification

Validation

Market Launch

TRUFORMA™ // Point-of-Care Biosensor PlatformThyroid & Adrenal Disorder Immunoassays

Zomedica has partnered with Qorvo Biotechnologies, LLC to collaborate on the development of a collection of rapid veterinary diagnostic assays with the goal to deliver reference-lab performance at the point of care. TRUFORMA™, formerly ZM-024, is expected to be comprised of a table-top instrument that uses disposable assay cartridges to test a range of samples including whole blood, serum, and plasma. Joint development work initially targets five assay candidates to detect certain thyroid and adrenal disorders in dogs and cats, which currently require reference lab immunoassay testing for reliable diagnostic results. TRUFORMA™ is an investigational device, not currently available for sale and limited to investigational use only. Verified Assays: Canine Total T4 Assays in Development: Feline Total T4, Feline TSH, Canine TSH, Canine Free T4, Canine Cortisol, Canine eACTH
Learn More Get the White Paper
ZM-020 // Point-of-Care Pathogen Detection PlatformUrine & Fecal Testing

Zomedica has partnered with Seraph Biosciences, Inc. to develop their in-clinic diagnostic analyzer for use in the detection of pathogens in companion animals. The ZM-020 diagnostic platform has the potential to screen for a wide range of pathogens in companion animal feces, urine, respiratory, and dermatological samples in minutes without the need for extensive sample prep or the use of reagents. The first tests Zomedica expects for release with the ZM-020 diagnostic platform will focus on the rapid detection of fecal parasites, potential UTI-associated urine bacteria and crystals, and leptospirosis using urine samples.
Get the White Paper
ZM-017 // Canine Cancer Liquid Biopsy PlatformHemangiosarcoma & Osteosarcoma

Zomedica has partnered with Celsee, Inc. to develop their circulating tumor cell (CTC) “liquid biopsy” platform for use by veterinarians as a canine cancer diagnostic. ZM-017 aims to enable veterinarians to detect canine cancers in a manner that is faster, more affordable and less invasive compared to existing methods, which can be expensive and cost prohibitive for pet owners. The first assay Zomedica expects for release with ZM-017 targets hard-to-diagnose canine cancers, such as hemangiosarcoma and osteosarcoma.
Get the White Paper

Assay Development
- ZM-020 // Point-of-Care Pathogen Detection PlatformUrine & Fecal Testing
  
  Zomedica has partnered with Seraph Biosciences, Inc. to develop their in-clinic diagnostic analyzer for use in the detection of pathogens in companion animals. The ZM-020 diagnostic platform has the potential to screen for a wide range of pathogens in companion animal feces, urine, respiratory, and dermatological samples in minutes without the need for extensive sample prep or the use of reagents. The first tests Zomedica expects for release with the ZM-020 diagnostic platform will focus on the rapid detection of fecal parasites, potential UTI-associated urine bacteria and crystals, and leptospirosis using urine samples.
  Get the White Paper
Verification
- TRUFORMA™ // Point-of-Care Biosensor PlatformThyroid & Adrenal Disorder Immunoassays
  
  Zomedica has partnered with Qorvo Biotechnologies, LLC to collaborate on the development of a collection of rapid veterinary diagnostic assays with the goal to deliver reference-lab performance at the point of care. TRUFORMA™, formerly ZM-024, is expected to be comprised of a table-top instrument that uses disposable assay cartridges to test a range of samples including whole blood, serum, and plasma. Joint development work initially targets five assay candidates to detect certain thyroid and adrenal disorders in dogs and cats, which currently require reference lab immunoassay testing for reliable diagnostic results. TRUFORMA™ is an investigational device, not currently available for sale and limited to investigational use only. Verified Assays: Canine Total T4 Assays in Development: Feline Total T4, Feline TSH, Canine TSH, Canine Free T4, Canine Cortisol, Canine eACTH
  Learn More Get the White Paper
Validation
- ZM-017 // Canine Cancer Liquid Biopsy PlatformHemangiosarcoma & Osteosarcoma
  
  Zomedica has partnered with Celsee, Inc. to develop their circulating tumor cell (CTC) “liquid biopsy” platform for use by veterinarians as a canine cancer diagnostic. ZM-017 aims to enable veterinarians to detect canine cancers in a manner that is faster, more affordable and less invasive compared to existing methods, which can be expensive and cost prohibitive for pet owners. The first assay Zomedica expects for release with ZM-017 targets hard-to-diagnose canine cancers, such as hemangiosarcoma and osteosarcoma.
  Get the White Paper
Market Launch

Therapeutics Pipeline

Formulation

Pilot Studies

Pivotal Studies

Final FDA-CVM
Review

Market Launch

*FDA-CVM Phased Review

Therapeutic Drugs //

ZM-007 Metronidazole Oral Suspension: Anti-Diarrheal for small breeds and puppies
ZM-012 Metronidazole Tablet: Anti-Diarrheal
ZM-007 and ZM-012 are complementary oral formulations of metronidazole targeting the treatment of acute diarrhea in dogs. ZM-007 is an oral suspension, currently only available via compounding pharmacies, for use with small dogs and puppies. ZM-007 and ZM-012 are complementary oral formulations of metronidazole targeting the treatment of acute diarrhea in dogs. ZM-012 is a tablet formulation currently only available as a human generic.

ZM-006 Transdermal Methimazole: Hyperthyroidism - Oral formulation approved for use in humans and cats.
ZM-006 is a transdermal gel formulation of methimazole targeting the chronic treatment of hyperthyroidism in cats. Intended for application to the cat’s ear, the transdermal gel is an alternative to conventional oral tablets already approved by the FDA Center for Veterinary Medicine for cats. Because of the associated difficulties with administering pills to cats, methimazole continues to be one of the most frequently compounded drugs in other dosage forms.

ZM-011 Transdermal Fluoxetine: Behavioral Disorders e.g. inappropriate urination, same API as Prozac®
ZM-011 is a transdermal formulation of fluoxetine intended to treat behavioral disorders, such as inappropriate urination, in cats. Intended for application to the cat’s ear, the transdermal gel is most commonly known by its human pharmaceutical brand name Prozac® and is currently only available as a human-approved oral tablet or compounded drug.

Formulation
Pilot Studies
- Therapeutic Drugs //
  
  ZM-007 Metronidazole Oral Suspension: Anti-Diarrheal for small breeds and puppies
  ZM-012 Metronidazole Tablet: Anti-Diarrheal
  ZM-007 and ZM-012 are complementary oral formulations of metronidazole targeting the treatment of acute diarrhea in dogs. ZM-007 is an oral suspension, currently only available via compounding pharmacies, for use with small dogs and puppies. ZM-007 and ZM-012 are complementary oral formulations of metronidazole targeting the treatment of acute diarrhea in dogs. ZM-012 is a tablet formulation currently only available as a human generic.
  
  ZM-006 Transdermal Methimazole: Hyperthyroidism - Oral formulation approved for use in humans and cats.
  ZM-006 is a transdermal gel formulation of methimazole targeting the chronic treatment of hyperthyroidism in cats. Intended for application to the cat’s ear, the transdermal gel is an alternative to conventional oral tablets already approved by the FDA Center for Veterinary Medicine for cats. Because of the associated difficulties with administering pills to cats, methimazole continues to be one of the most frequently compounded drugs in other dosage forms.
  
  ZM-011 Transdermal Fluoxetine: Behavioral Disorders e.g. inappropriate urination, same API as Prozac®
  ZM-011 is a transdermal formulation of fluoxetine intended to treat behavioral disorders, such as inappropriate urination, in cats. Intended for application to the cat’s ear, the transdermal gel is most commonly known by its human pharmaceutical brand name Prozac® and is currently only available as a human-approved oral tablet or compounded drug.
Pivotal Studies FDA-CVM Phased Review
Final FDA-CVM Review FDA-CVM Phased Review
Market Launch